Simultaneous stability of short alternating Z and B helices in synthetic DNA concatamers.

نویسندگان

  • F Quadrifoglio
  • G Manzini
  • K Dinkelspiel
  • R Crea
چکیده

The conformation of d(TA)3 (CG)3 has been studied in aqueous solution in the presence of high salt concentration. The oligonucleotide forms in solution concatamers. In the presence of 5 M NaC1 the concatamer is built up of d(CG)3 blocks in Z-conformation and of d(TA)3 blocks in B-conformation. In the presence of 4 M LiCl both blocks in the concatamer display a B-type structure.

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عنوان ژورنال:
  • Nucleic acids research

دوره 10 12  شماره 

صفحات  -

تاریخ انتشار 1982